Oncology Informatics & AI

Where Cancer Medicine Meets Technology

Independent analysis for oncology leaders navigating AI, clinical informatics, and technology transformation. No vendor ties. No sponsored content.

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Jivesh Sharma, M.D.

Medical Oncologist · CEO, Nexgen Precision · MIT Sloan AI Certificate

Featured

deep-dive

The Payer-Provider AI Arms Race Is the Wrong Frame

Health systems build AI to fight denials. Payers build AI to issue them. This adversarial equilibrium doesn't reduce cost — it redistributes it into compute. The actual unlock is structural.

March 21, 2026 · 8 min read

Latest Analysis

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deep-dive

Agentic Prior Authorization in Oncology: From Denial Theatre to Decision Logic

Oncology prior authorization is a natural beachhead for agentic AI: high-volume, evidence-bound work with asymmetric patient stakes.

May 8, 2026 · 7 min read

framework

The Clinical Floor for AI Validation: HealthBench, RAVE, and What's Missing

Healthcare AI validation needs more than benchmark performance. The clinical floor is source-grounded, audited, local, and monitored.

May 8, 2026 · 6 min read

tutorial

TEFCA + FHIR for Oncology: The Data Spine That Makes Agentic Care Possible

TEFCA and FHIR are the boring infrastructure behind serious oncology AI. Without longitudinal interoperability, the agent is blind.

May 8, 2026 · 7 min read

deep-dive

Foundation Models in Precision Oncology: Where the Evidence Actually Is

Foundation models are reshaping precision oncology, but the evidence is uneven across genomics, pathology, imaging, and narrative.

May 8, 2026 · 7 min read

The Podcast

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EP 24 · 42 min

Fast Takeoff in Healthcare: Why This Time Is Different

The compounding dynamics that make 2026 the inflection point for clinical AI deployment.

EP 23 · 38 min

Validating AI Agents Before They Touch Patients

Frameworks for testing agentic systems in oncology — what the FDA isn't telling you.

EP 22 · 51 min

The EMR Is Dead. What Replaces It?

From iKnowMed to ambient AI — a 30-year view on what clinical software should actually do.

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